Oncology Journal of India

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 4  |  Issue : 2  |  Page : 67--72

Bacterial vaginosis and its association with human papilloma virus and increased risk of cervical intraepithelial lesions: An experience from Eastern India


Bhagyalaxmi Nayak1, Pallavi Patnaik1, Manoranjan Mohapatra1, Dhananjaya Soren2, Priyadarshini Patra3, Kusumbati Besra4, Sushil Kumar Giri1 
1 Department of Gynaecological Oncology, Acharya Harihar Post Graduate Institute of Cancer, Cuttack, Odisha, India
2 Department of Zoology, Revenshaw University, Cuttack, Odisha, India
3 Department of Microbiology, S.C.B. Medical College, Cuttack, Odisha, India
4 Department of Pathology, S.C.B. Medical College, Cuttack, Odisha, India

Correspondence Address:
Manoranjan Mohapatra
Department of Gynaecological Oncology, Acharya Harihara Post Graduate Institute of Cancer, Cuttack - 753 007, Odisha
India

Background: Bacterial vaginosis (BV) is the most common vaginal disorder affecting women of reproductive age and has an influence in acquisition of certain genital infections. However, it is difficult to determine whether BV is actually a risk factor for human papilloma virus (HPV) acquisition or not and whether it may lead to cervical cancer. Aim of the Study: The aim of the present study is to determine the prevalence of BV and its association with HPV infection and cervical intraepithelial neoplasia (CIN). Materials and Methods: A multiinstitutional prospective study was conducted to analyze the vaginal samples collected from the women aged between 19 and 49 years during the period from December 2014 to January 2018. Results: A total of 333 women with vaginal samples were analyzed for BV. 103 (30.93%) samples were diagnosed with BV as per Amsel's criteria. The prevalence of HPV DNA was higher in BV-positive cases in comparison to that of BV-negative cases (44.7% vs. 9.6%; P = 0.000) showing a significant association between BV and HPV infection. There was a rising trend in the incidence of CIN for women diagnosed with BV when compared to BV negative women (62.1% vs. 43%; P = 0.506), although statistically insignificant. Moreover, the severity/high grading of CIN was not significantly associated with BV (P = 0.765). Conclusion: The result of our study hypothesized that BV was significantly associated with increased risk of HPV infection. There was a rising trend for the association of BV with CIN incidence although statistically insignificant.


How to cite this article:
Nayak B, Patnaik P, Mohapatra M, Soren D, Patra P, Besra K, Giri SK. Bacterial vaginosis and its association with human papilloma virus and increased risk of cervical intraepithelial lesions: An experience from Eastern India.Oncol J India 2020;4:67-72


How to cite this URL:
Nayak B, Patnaik P, Mohapatra M, Soren D, Patra P, Besra K, Giri SK. Bacterial vaginosis and its association with human papilloma virus and increased risk of cervical intraepithelial lesions: An experience from Eastern India. Oncol J India [serial online] 2020 [cited 2020 Nov 23 ];4:67-72
Available from: https://www.ojionline.org/article.asp?issn=2589-1871;year=2020;volume=4;issue=2;spage=67;epage=72;aulast=Nayak;type=0