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CASE REPORT
Year : 2021  |  Volume : 5  |  Issue : 1  |  Page : 36-38

Sarcomatoid carcinoma of the larynx: An aggressive tumor


1 Department of Pathology, Tata Memorial Centre, Homi Bhabha Cancer Hospital, Varanasi, Uttar Pradesh, India
2 Department of Head and Neck Oncology, Tata Memorial Centre, Homi Bhabha Cancer Hospital, Varanasi, Uttar Pradesh, India

Correspondence Address:
Bhagat Singh Lali
Department of Pathology, Tata Memorial Centre, Homi Bhabha Cancer Hospital, Varanasi - 221 010, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/oji.oji_29_20

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Sarcomatoid carcinoma of the larynx is a rare and aggressive tumour with a unique biologic behavior and histogenesis. They were earlier called as collision tumors. They are classified under “epithelial tumors” in the World Health Organization classification. Due to the aggressive clinical behavior, they obstruct the airways soon and the patients present early. We present a case of a 55-year-old female who presented in acute state to the emergency department with dyspnea. On evaluation, a locally advanced laryngeal malignancy was detected radiologically. The biopsy was performed wherein a spindle cell pleomorphic tumor was seen which was positive for AE1/AE3 and vimentin, thus rendering a final diagnosis of sarcomatoid carcinoma. We discuss the clinical features, biological behavior, and management of these rare carcinomas.


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