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Year : 2017  |  Volume : 1  |  Issue : 2  |  Page : 40-42

Vaginal primary amelanotic melanoma with survival beyond expectation: A rare case report

1 Department of Gynaecological Oncology, Acharya Harihar Regional Cancer Centre, Cuttack, Odisha, India
2 Department of Pathology, Acharya Harihar Regional Cancer Centre, Cuttack, Odisha, India

Correspondence Address:
Bhagyalaxmi Nayak
Department of Gynaecological Oncology, Acharya Harihar Regional Cancer Centre, Cuttack - 753 007, Odisha
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/oji.oji_18_17

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Vaginal malignancies are uncommon, constituting 1%–2% of all the female genital tract malignancies. Even rare are melanomas of the vagina with an annual incidence of 0.026/100,000 women worldwide, and amelanotic variant constitutes only 2% of all the vaginal melanomas. Here, we report a case of primary vaginal amelanotic melanoma in a 70-year-old woman, initially treated with wide local excision followed by adjuvant chemotherapy. After six and half years of follow-up, the patient developed a recurrence in the left inguinal nodal region with a suspicious pulmonary nodule and is now under treatment. Amelanotic melanoma has varied clinical presentation and microscopic appearance with the absence of characteristic pigmentation, leading to a diagnostic delay and thus carries a poor prognosis. Therefore, it is prudent to have a high index of suspicion for these rare tumors. Hence, we report this case of primary vaginal melanoma, amelanotic variant with a surprisingly long survival of nearly 7 years for information and pertinent discussion.

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