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Year : 2019  |  Volume : 3  |  Issue : 3  |  Page : 66-69

Dermatofibrosarcoma protuberans, lymphedema, and breast cancer: A rare association

1 Department of Radiation Oncology, CMC, Vellore, Tamil Nadu, India
2 Department of Pathology, CMC, Vellore, Tamil Nadu, India
3 Palliative Care Unit, CMC Hospital, Vellore, Tamil Nadu, India

Correspondence Address:
Dr. Kaalindi Singh
Department of Radiation Oncology, CMC Hospital, Vellore, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/oji.oji_26_19

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A woman with postmastectomy lymphedema presented with a progressive nodular swelling on the affected limb. The biopsy was reported as dermatofibrosarcoma protuberans (DFSP). There is only one other case in literature, where a truncal dermatofibrosarcoma was reported in association with breast cancer. Both tumors had the P53 mutation. In our patient, the breast cancer and the DFSP were both negative for the P53 mutation and it is possible that chronic lymphedema was causative in the formation of the DFSP. More evidence is needed to understand the etiopathogenesis of DFSP occurring in breast cancer patients.

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